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Because the two peptides have different half-lives, combined protocols described in the literature typically reflect their different dosing frequencies

For instance, two siblings both harboring the same mitochondrial mutation causing Lebers hereditary optic neuropathy had markedly different clinical courses: the brother exhibited typical progressive optic neuropathy whereas the sister suffered from a relapsingremitting MS-like illness (Joshi and Kermode, 2019)

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However, your physician will determine the appropriate dosage and frequency based on factors such as your health status, desired outcomes, and response to treatment