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Unlike the reigning blockbuster GLP-1 drugs on the market namely Novo Nordisks Wegovy (semaglutide) and Eli Lillys Zepbound (tirzepatide), the latter of which is a dual agonist of the GLP-1 and GIP receptors Amgens MariTide is an antibody-peptide conjugate that combines a GLP-1 receptor agonist (consisting of two peptides that mimic the GLP-1 hormone) and GIP receptor antagonist (an antibody that blocks the receptor)

treat promptly per standard of care, and monitor until signs and symptoms resolve

The most advanced out of all of them is phase 2 candidate aleniglipron

Diagnosis and classification of diabetes: standards of care in diabetes-2024