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A 2023 review published in Nature Reviews Endocrinology by Muller et al
Because it is a newer, patent-protected drug, there is currently no cheap generic version available, and experts dont expect one until the early 2030s
Gewebe, der die gemeinsame Endstufe fr Monosaccharide, Fettsuren und Aminosuren darstellt, werden durch zwei Dekarboxylierungsreaktionen die in den Zyklus eintretenden C-6-Verbindungen (Zitronensure) whrend eines Umlaufs im Zyklus zu C-4-Verbindungen (Oxalessigsure) abgebaut, die Kohlenstoffkette wird also um zwei Kohlenstoffatome verkrzt.In the metabolic cycle of healthy cells or tissues, which is the common end stage for monosaccharides, fatty acids and amino acids, the C-6 compounds (citric acid) entering the cycle become C-4 compounds (oxaloacetic acid) during one cycle in the cycle through two decarboxylation reactions ) degraded, so the carbon chain is shortened by two carbon atoms
This constitutes a medical emergency requiring immediate assessment
