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Why This Result Was Unexpected Tirzepatide produces ~50% more weight loss than semaglutide in head-to-head trials (SURPASS-2, SURMOUNT-5)
Wall Street called the selloff overdone. BMO Capital Markets analysts noted that with insured individuals in the US already paying as low as $25/month for GLP-1 medications, we continue to view any ultimate negotiated MFN price as more of a headline risk versus a true fundamental change to the companies businesses
(2014) 3:e93799
Instead, the results suggest that some DM2 DMTs act through indirect, metabolic, or context-dependent mechanisms rather than direct neuroprotection
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