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So, GLP peptides, again, glucagon-like peptide is naturally secreted in the human body
They are particularly valuable for patients with established cardiovascular disease, heart failure, or chronic kidney disease
Several medical organizations have advised caution regarding compounded GLP-1 therapies, particularly when products originate from poorly regulated sources
In the phase 2 NEJM trial, participants receiving the highest dose of retatrutide (12 mg) achieved a mean body weight reduction of approximately 24.2% from baseline at 48 weeks, compared with approximately 2.1% in the placebo group
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