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The effects of DBD treatments on promotion of cancer cells apoptosis 12,13 , proliferation of osteoblasts 14,15 , inactivation of enzymes 16,17 and oxidative conversion of organic molecules 18,19 are deeply investigated

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Activation of the 2 -adrenergic pathway is the main mechanism by which insulin secretion is inhibited by the SNS 21 hence our strategy was to activate 2 adrenergic receptors on pancreatic -cells to test if this would counteract the hypothesised decrease in SNS activity triggered by OB GLP-1R activation in WD mice

doi:10.1177/1099800419898002