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An investigation into the antimicrobial biofilm activity of poultry erythrocyte histones against methicillin-sensitive S.aureus (MSSA) and methicillin-resistant S.aureus (MRSA) indicated that both histones and indolicidin (used as a positive control) upregulated the expression of apsS and apsR, genes involved in the antimicrobial peptide (AMP) sensor/regulatory system in S.aureus
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