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In summary, from modulating microglial polarization and neutralizing pro-inflammatory cytokines, to targeting immune checkpoints and astrocyte-derived inhibitory pathways, immunomodulatory strategies offer multifaceted approaches to disrupt the ferroptosisinflammation interplay

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A combination of NAC with -lipoic acid (also an antioxidant) and bromelain prevents upregulation of the VCAM1 inflammatory marker, promotes apoptosis of endometriotic but not normal uterine cells, and reduces the size and number of endometriotic lesions in mice (167)

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