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Because it stimulates the bodys own growth hormone production, dosing needs to stay within physiologic limits to avoid excess IGF-1. If levels climb too high, she notes, you might get symptoms such as fluid retention, joint stiffness, carpal tunnellike numbness, or mild insulin resistance, though these effects are uncommon with conservative dosing and regular monitoring
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10.1097/HS9.0000000000000165 79
Review article: Putting some muscle into sarcopenia-the pathogenesis, assessment and clinical impact of muscle loss in patients with inflammatory bowel disease
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