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Dietary modifications support tolerance: increase soluble fiber gradually, stay well hydrated (at least 23 liters daily), limit high-fat foods that accelerate transit, and eat smaller, more frequent meals

These tests can effectively be used to study the behavior of peptides, their interaction with receptors, and molecular pathways in preclinical laboratory experiments

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Global assessment of the evidence The Modified Bradford Hill Criteria was used to assess the potential relationships among various available evidence [33,34,35]