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Although it had been confirmed that GLP-1RAs had excellent therapeutic effects in the treatment of RA, how to enrich it in the pathological microenvironment of arthritis and avoid off-target effects of the drug was the main challenge currently faced
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The black box warning on GLP-1 receptor agonists stems from animal studies showing C-cell hyperplasia and medullary thyroid cancer in rodents
This skips over any absorption problems
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