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SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense

5 Conclusions and perspectives With its fast-growing cells in a sterile system, the use of a root cell culture is an appropriate alternative for xenobiotic metabolism studies to evaluate and understand basic detoxification mechanism and set up an analytical method for new xenobiotic compounds in a plant matrix

H., Rehman, K

These studies generally demonstrate favorable safety profiles, although their therapeutic efficacy is often limited by poor aqueous solubility, rapid metabolism, and low systemic bioavailability