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Stacked Protocol (AOD + MOTS-c) Dose: 0.5 mg AOD + 10 mg MOTS-c (= 20 clicks) Duration: 4 weeks Frequency: Daily Cycle Interval: Optional 2-week pause Goal / Description: 2 weeks off, then repeat or switch to MOTS-c only maintenance Possible Side Effects AOD-9604 is generally well-tolerated in research settings
MDR can be mediated by high-mobility box group 1 (HMGB1), which promotes protective autophagy against anticancer agents
Core patents were set to expire in 2026, but the company has secured additional protections on the formulation and dosage that could extend exclusivity in the U.S
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