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This could have promising outcomes for age-related conditions and cardiovascular disease
Acrolein can react and form adducts with DNA, lipids and proteins leading to cellular damage in several human tissues
This cycling approach helps prevent desensitization and maximizes benefits 1
Interestingly, despite their inhibitory effect on the isolated TOP2A activity, CYS did not show any reduction of cell viability in their tested solubility range (20 M) for any tested human and non-human cell line (Fig
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