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When lifestyle measures prove insufficient, laxatives may be appropriate: Osmotic laxatives (macrogol/polyethylene glycol preparations) are often considered first-line for chronic constipation

PlexusDx offers compounded tirzepatide injections at $289/mo month-to-month, or from $249/mo on the 6-month plan and can help determine if a switch is warranted

The FLOW trial demonstrated a 24% reduction in kidney disease progression in patients with type 2 diabetes and chronic kidney disease taking semaglutide