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Galectin Therapeutics Inc, Cirius Therapeutics Inc, Inventiva Pharma SA, Akero Therapeutics Inc and Theratechnologies Inc, are also moving their NASH therapeutic candidates into later stage clinical development, encouraged by patient outcomes, safety profiles and the hitting of key endpoints in early clinical studies
In this population, oral semaglutide 50 mg induced clinically meaningful reductions in body weight, with accompanying improvements in cardiometabolic risk factors. The study was simultaneously released at the American Diabetes Association 2023 Scientific Sessions alongside several other presentations testing oral formulations in diabetes (PIONEER PLUS) as well as a new dual glucagon (GCG) receptor and GLP-1 receptor drug, survodutide, and the triple-targeting retatrutide, which acts on GLP-1, GCG, and glucose-dependent insulinotropic polypeptide (GIP)
The academic research was obtained from PubMed database, with exclusion criteria from articles published no more than 5 years ago (2013-2018), found useful to work 119, previously mentioned
Two of the most talked-about medications in this area are Mounjaro and Ozempicboth injectable treatments that have demonstrated impressive results in clinical studies
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