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Common symptoms include nausea, constipation, diarrhea, bloating, and appetite suppression
However, the triple-hormone receptor agonism of retatrutide may bring additional benefits, potentially leading to more improvements in these parameters
Elderly patients may experience both migraines and conditions for which tirzepatide is beneficial, but they also face higher risks of dehydration, hypoglycemia, and medication interactions
Thus, GLP-1 could improve hepatic lipid metabolism by regulation of NAMPT/SIRT1/AMPK signaling
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