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Blocking IL-6 receptor had reduced the pathogenicity of DCM and interstitial fibrosis by inhibiting SOCS -3, an immune signalling marker (92)
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Average weight loss after 48 weeks included: 1 mg dose: about 8.7% body-weight reduction 4 mg dose: about 17.1% reduction 8 mg dose: about 22.8% reduction 12 mg dose: about 24.2% reduction Placebo: about 2.1% reduction These results represented one of the largest average weight reductions reported for an antiobesity medication in a randomized clinical trial
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