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The isoelectric point (pI) was calculated at 5.35 for nGLP1-DARPin and mGLP1-DARPin-1 and 5.01 for mGLP1-DARPin-2, indicating the dominance of amino acids with negative charges
In addition to chronic weight management, orforglipron is being studied as a potential treatment for Type 2 diabetes, obstructive sleep apnea, osteoarthritis knee pain, hypertension, peripheral artery disease, and stress urinary incontinence
Caution is advised in those with a history of pancreatitis
Ozempic is one of many medications in the GLP-1 agonist class used to treat type 2 diabetes
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