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However, exclusive use of folic acid in treating vitamin B12 deficient megaloblastic anemia could result in progressive and irreversible neurologic damage

Combination therapy provides the best outcomes

The clinical applications in physician-supervised contexts include improved body composition, enhanced lean mass preservation, improved sleep quality (GH is released primarily during deep sleep and is essential for tissue repair), accelerated recovery from exertion and injury, and metabolic support

Therefore, erythrophagocytosis-induced ferroptosis contributes to the formation of larger atherosclerotic plaques, but this effect can be reversed by UAMC-3203 (Puylaert et al., 2023)