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It was discovered and extracted from muscle in 1905
The mobile phase system consisted of two phases, phase A (water) and phase B (water/acetonitrile, 1:9, v/v), and 10 mM of ammonium acetate was added to both of the phases
The peptide demonstrates remarkable stability compared to other compounds in its class
MT-IIs MC3R and MC4R activation in hypothalamic energy balance circuits produces significant and dose-dependent food intake reductions
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