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doi: 10.1038/s41591-018-0131-6 141 HorvatiAGelemanoviAPirkiBSmolecOBeer LjubiBRubiIet al

Other Considerations Recent or planned major surgery : Due to effects on digestion and nutritional intake, these medications may not be appropriate around the time of major surgery

But some studies have focused on adults with a history of Major cardiovascular disease

Patients should be counseled about symptoms that might suggest thyroid pathology, including neck mass, dysphagia, hoarseness, or persistent cough, and instructed to report these promptly