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Quercetin prevented VPA-induced behavioral impairments and attenuated oxidative alterations across multiple brain regions, supporting its antioxidant and neuroprotective potential in this ASD model ( Since quercetin itself in low concentrations is poorly absorbed, can hardly cross the BBB and is quickly eliminated, the study of Moghaddam used quercetin-loaded nanophytosome (QNP) against autism-like damage in maternal separation model
Unlike GLP-1 agonists, the changes are compositional rather than scale-weight driven: patients may not lose significant total body weight but will show meaningful reduction in waist circumference and visceral fat volume
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Accumulation of toxins in the body and increased oxidative stress, which also leads to premature aging
