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Myth 3: Glutathione is unsafe Truth: Generally safe when taken correctly

The Grx family of proteins plays a key role in the regulation of glutathionylation reactions ( Figure 3

Other indicators include a family history of pernicious anaemia or other autoimmune conditions (such as type 1 diabetes mellitus, Hashimotos thyroiditis, or Graves disease), or if the patient is taking metformin, proton pump inhibitors (PPIs), H2 antagonists or has a history of nitrous oxide misuse[15]

Despite these benefits, long-term LC administration has been associated to cardiovascular risks due its conversion to trimethylamine- N -oxide (TMAO) by the gut microbiota