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d-Allulose decreases food intake via GLP-1R signaling To assess whether GLP-1 mediates d-allulose-induced inhibition of food intake we used a GLP-1R antagonist, exendin(9-39) (Ex(9-39))

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S2CID 2209805

Reported Sex-Based Variability in the Literature Where sex-based data does appear, researchers generally attribute observed variability to differences in baseline endogenous IGF-1 and growth hormone signaling between male and female physiology, rather than to any fundamental difference in how IGF-1 LR3 binds or activates the IGF-1 receptor