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Mitochondrial dysfunction is hypothesized to be a factor in the pathogenesis of both CVS and migraine headache based upon decreased respiratory complex enzymology, disease-associated mitochondrial DNA (mtDNA) sequence variants, and preferential maternal inheritance [reviewed in 5]
Cullen, J.J., Mitros, F.A
doi: 10.1046/j.1365-2125.2003.01907.x Georges Delpre, Pinhas Stark, Yaron Niv, Sublingual therapy for cobalamin deficiency as an alternative to oral and parenteral cobalamin supplementation, The Lancet, Volume 354, Issue 9180, 28 August 1999, Pages 740-741, ISSN 0140-6736,
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