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This condition occurs when blood flow to a part of the heart is blocked
Biol Psychiat 93(12):10891098 Faulkner P, Paioni SL, Kozhuharova P et al (2021) Relationship between depression, prefrontal creatine and grey matter volume
Importantly, these models often integrate both up- and down-regulated compounds, emphasizing the diagnostic value of relative metabolic balance over absolute concentration shifts
If you are experiencing persistent GI symptoms while on one of these medications, a consultation with a gastroenterologist can help determine whether adjustments or further testing are needed
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