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Glucagon-like peptide-1 in the rat brain: distribution of expression and functional implication

Advanced Biomedical Research , 3, 162

Preclinical research evidence Animal Experiments Obese mouse model: After subcutaneous injection of AOD 9604 (250 g/kg) daily for 8 weeks, the body weight of obese mice decreased by 12%, the subcutaneous fat mass decreased by 25%, and the weight of epididymal adipose tissue decreased significantly

The C16orf87 amino acid sequences are highly conserved across human and mouse (99% sequence identity), and there is also a high degree of conservation between the human and zebrafish C16orf87 amino acid sequences (~ 75% sequence identity