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[2] Antioxidant enzymes, such as glutathione peroxidases and peroxiredoxins, generate glutathione disulfide during the reduction of peroxides such as hydrogen peroxide (H 2 O 2 ) and organic hydroperoxides (ROOH): [3] 2 GSH + ROOH GSSG + ROH + H 2 O Other enzymes, such as glutaredoxins, generate glutathione disulfide through thiol-disulfide exchange with protein disulfide bonds or other low molecular mass compounds, such as coenzyme A disulfide or dehydroascorbic acid
Clinical Significance of Folate Deficiency Folate deficiency results in complications nearly identical to those described for vitamin B12 deficiency
Glutathione in these fractions were alkalized and derivatized with 6-aminoquinolyl-N hydroxy succinimidyl carbamate as described previously
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