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In the SURMOUNT-1 trial, adults taking injectable tirzepatide lost an average of about 15% with the 5 mg dose, 19.5% with the 10 mg dose, and 20.9% to 22.5% with the highest 15 mg dose after 72 weeks

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While necessary, this phase transforms toxins into "reactive intermediate metabolites" that are frequently more toxic and volatile than the original substance, generating massive amounts of free radicals

Of course, were still early: Most studies are small or preclinical Larger clinical trials are needed Access, cost, and safety must be considered But this could represent a real shift in how we think about treating addiction not just as a behavioral condition, but as one deeply tied to metabolic and brain pathways