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Zygote (2017) 25:16875
Each approach has genuine trade-offs
The four-pathway model therefore targets appetite (GLP-1 and amylin through separate neuronal circuits), fat metabolism (GIP and glucagon), energy expenditure (glucagon primarily), and glucose homeostasis (GLP-1, GIP, and amylin all contribute through different mechanisms)
10002000 g daily) can correct deficiency in some cases (even without intrinsic factor, because a small fraction can be absorbed passively)
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