Pay in 4 interest-free payments of $6.58 Learn more
Ships within 48 hours · Estimated delivery Sep 3 - Sep 8
Although the reduced food intake stimulated by tirzepatide is considered to be the main contributor to the reduced body weight,30 other mechanisms, including increased energy expenditure induced by tirzepatide, may contribute to the reduced body weight and liver fat content.1, 31 An ongoing clinical trial whose main purpose is to investigate the effect of tirzepatide on energy expenditure and food intake in obese patients (NCT04081337) will provide more information on the mechanism by which tirzepatide treatment reduces body weight
doi:10.1111/ppc.13043
Why Glucagon Matters Glucagon increases energy expenditure through thermogenesis, promotes hepatic fat oxidation (burning liver fat directly), mobilizes fat from adipose tissue, and reduces food intake through pathways separate from GLP-1
Flanagan JL, Simmons PA, Vehige J, Willcox MD, Garrett Q: Role of carnitine in disease
