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GH secretion was increased after CJC-1295 administration with preserved pulsatility confirming that continuous GHRH-receptor stimulation enhances both trough and mean GH secretion while maintaining the pulsatile architecture essential for physiological GH axis function
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The drug is a modified version of human GLP-1, with a fatty acid chain attached that allows it to bind to albumin in the blood, extending its duration compared to natural GLP-1 (which lasts only minutes)
