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Hyperglycemia leads to increased mitochondrial ROS production in endothelial cells, exacerbating oxidative stress
However, weight loss induced by GLP-1RAs encompasses both fat and lean tissue compartments and could be associated to nutritional deficiencies, raising important questions regarding their impact on skeletal muscle, particularly in individuals at increased risk of sarcopenia [11]
Obesity (Silver Spring, Md.) , 22 (10), 22672273
International Journal of Sciences: Basic and Applied Research (IJSBAR)
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