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Additionally, such systems are well suited for the screening of permeability coefficients (Wolff et al., 2015)
Most do not have the potency needed
However, these drugs are limited: They slow but do not reverse fibrosis, they are poorly tolerated, and it remains to be established whether they are translatable to other fibrotic inflammatory disorders, highlighting the clinical unmet need for alternative targeted anti-fibrotic strategies
Moreover, the higher the blood sugar, the less the body restores its own antioxidant reserves
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