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While highly effective for weight loss, clinical trials show that 2050% of patients experience some form of gastrointestinal side effect during the first weeks of treatment
When this barrier is compromised by nonsteroidal agents like ibuprofen (which block the good prostaglandins that make mucous), it can create ulceration and decrease peptide secretion from the gut
Prompt evaluation ensures that serious underlying conditions, including colorectal malignancy, inflammatory bowel disease, or significant gastrointestinal bleeding, are not missed
Is one injection site better than the other
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