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46 High intratumoral expression of CYP3A4 can accelerate the metabolic inactivation of chemotherapeutic agents such as paclitaxel and docetaxel, thereby reducing local drug bioavailability, diminishing therapeutic efficacy, and ultimately contributing to drug resistance
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doi: 10.1515/CCLM.2003.032 249 Decreased consumption of corticosteroids after selenium supplementation in corticoid-dependent asthmatics
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