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TB-500 operates systemically as a **cytoskeleton remodeler**: its primary function is G-actin monomer sequestration (active N-terminal Ac-Ser-Asp-Lys-Pro), its cleaved AcSDKP sequence is an **autonomous angiogenic factor**, it upregulates laminin-5 and matrix metalloproteinases (MMPs), and mobilizes mesenchymal progenitor cells

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and Rodushkin, I (2013) The benefits and risks of consuming brewed tea: Beware of toxic element contamination, Journal of Toxicology, ID 370460 [online] Available at: Shirishi, M., Haruna, M., Matsuzaki, M., Ota, E., Murayama, R., Sasaki, S., Yeo, S., and Murashima, S