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At 48 weeks, the 12 mg arm produced average losses of about 24% of baseline weight, 8 mg gave reductions of ~1718%, and 4 mg delivered double-digit but more moderate decreases

Key takeaways Wegovy, an injectable weight-loss drug, helps reduce hunger and food intake by mimicking the hormone GLP-1

It also may help you lose weight indirectly, because it can improve sleep, which makes it easier for people to maintain lifestyle changes like eating a healthier diet and being more active, she explains

Berberine and semaglutide represent two distinct approaches to metabolic healthone a plant alkaloid with glucose-lowering properties, the other a GLP-1 receptor agonist used for weight loss and blood sugar management