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# FDA Removes 12 Peptides from Category 2 Restrictions: What Changed in April 2026 In April 2026, the FDA announced it would remove 12 popular peptides from Category 2 restrictions including some of the most widely used compounds in biohacking, regenerative medicine, and peptide therapy circles
Frustrated by chronic joint pain, muscle tears, or a slow, painful post-surgical recovery
Unlike synthetic Wnt agonists, which can create unwanted off-target stimulation, the tripeptide appears to nudge Wnt signaling within a biological operating range
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