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Glucose-6-phosphate is oxidized to 6-phosphogluconolactone by glucose-6-phosphate dehydrogenase (G6PD) with the transfer of two electrons to NADP+ to form NADPH
137 Although recent studies support a role for NLRP3 inflammasomes in APAP-induced liver injury, the discrepancies and complexity of available data underscore the need for further research
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Inhibition of TrxR1 activity increases Nrf2 activity, ultimately leading to an increase in antioxidant production [14, 15]
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