can tirzepatide cause neuropathy reduces food intake and appetite, and affects brain functioning, more than placebo and liraglutide Causes and consequences of discontinuation

In the WASID trial (Warfarin-Aspirin Symptomatic Intracranial Disease), warfarin (target INR, 23) compared with aspirin 650 mg twice a day was found to have a higher rate of major hemorrhages (relative difference, 5.1%) and all-cause death (relative difference, 5.4%) but did not prevent more primary end points (stroke, ICH, vascular death) (22% in both arms at a mean follow-up of 1.8 years) or ischemic strokes in the territory of the stenotic artery (2-year rate: 15% for aspirin versus 13% for warfarin)

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doi: 10.1034/j.1399-3003.2000.016003534.x 229 RingelJ.RamlowA.BockC.SheriffA

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