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Wani, M
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FAHF-2-treated mice had improved clinical and immunological parameters, including decline in weight loss, improvement in histology, and inhibition of tumor necrosis factor (TNF)-, IL-17, IL-6, and IFN- production [41]
The role of oxidative stress in the COVID-19 disease may involve recognition of the viral S-protein by angiotensin converting enzyme-2 (ACE2) receptor and pattern recognition receptors like toll-like receptors 2 and 4, and activation of transcription factors like nuclear factor kappa B, that subsequently activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) expression succeeded by ROS production (Kozlov et al., 2021)
