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Note: an older GLP-1, liraglutide (Saxenda) , is also approved for weight management but is being discontinued as newer options take over
Among the notable mechanisms of action common to why this peptide has such powerful neuroprotective effects is chiefly the anti-inflammatory functions of GLP-1
Gene sets related to the MAPK and mTOR signaling pathways were retrieved from the Molecular Signatures Database (MSigDB) via the msigdbr R package
Cairns SP, Borrani F
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