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Benefit from it as much as possible while staying safe by beginning at low doses and titrating up in small increments, maintaining a consistent administration window

This makes them highly effective for diabetes and weight management

SGLT2 inhibitors appear more effective in mitigating glomerular hyperfiltration and lowering heart failure risk, whereas GLP-1 receptor agonists are particularly beneficial in reducing albuminuria and atherosclerotic cardiovascular events

The exact molecular mechanisms leading to WL and glycaemia improvements with tirzepatide are still under investigation, mainly because the role of GIP receptor activation with tirzepatide is unclear