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The axis formed between the centroid point on the nostril plane and the peripheral point on the circle determined the new perturbed direction (PD)

Although lactylation modifications have been demonstrated to regulate ferroptosis across diverse experimental models, it remains unclear whether these mechanisms are restricted to the specific disease contexts and models studied or can be universally extended to all cellular systems

Exactly the same principle

Our results indicated that neither GHK nor GHK-Cu showed cytotoxic activity at the range of concentrations tested while CuCl 2 and Cu(OAc) 2 showed substantial cytotoxicity to the HaCaT cells at the highest concentration assayed, i.e., at 5800 M, after 30 mins treatment