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J Neuropathol Exp Neurol 59:314322

The protocol successfully generated hepatocytes from cGMP cell lines using small molecules combined with growth factors in 21 days ( ALB expression was detected but insignificant in the induced hepatocytes, suggesting that the hepatocytes was immature ( ALB positive hepatocytes account for 67.7% versus 37.1% in the growth factor group ( 3.2 Small molecules for direct reprogramming to hepatic lineage Recently, studies have shown that somatic cells can be directly reprogrammed into specific cell lineage, including hepatocytes

A clinical study using DSIP in chronic insomnia patients reported significant improvements in sleep onset latency and subjective sleep quality at doses as low as 25 nmol (approximately 90 mcg) (Schneider-Helmert & Schoenenberger, 1983

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