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The phase 3 TRIUMPH-4 data showed these rates at 9 mg and 12 mg doses respectively: Nausea: 38.1% and 43.2% (vs 10.7% placebo) Diarrhea: 34.7% and 33.1% (vs 13.4% placebo) Constipation: 21.8% and 25.0% (vs 8.7% placebo) Vomiting: 20.4% and 20.9% (vs placebo) These numbers are higher than cagrilintide monotherapy across the board
They are not permanent and need maintenance to sustain
The physicochemical characteristics of the liposomes, including particle size, polydispersity, and zeta potential, were later analyzed as previously described (de Castro et al
Presented for research literature review only Balthrop JE et al
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