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1 H NMR (400 MHz, DMSO- d 6 ), (ppm): 8.41 (s, 1H), 7.76 (d, 2H), 7.197.25 (m, 11H), 7.007.09 (m, 6H)
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In parallel, methods to precisely modify the genome of hiPSCs, for instance to insert or repair disease-relevant mutations or lineage-tracing markers, and to produce neural cells and tissues in vitro that reflect the complexity of the native environment, have become increasingly sophisticated
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