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However, combining transcriptomics data from RNA-seq with paired metagenomic analysis allows the identification of specific host pathways that are activated or suppressed in response to microbial interactions

It is also possible that riboflavin exerts its antioxidant effect by reinforcing the effect of other antioxidants such as vitamin C ( Reference Rao and Bhat 29 )

However, to truly translate these potential strategies into clinically feasible bone protection plans, more systematic and comprehensive translational research is still needed

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